論文・総説・著書・その他出版物等
学会発表・講演等
特許・特許出願
報道等
論文・総説・著書・その他出版物等
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
2001
2000
▲PAGE TOP
2021年
Shigeno T., Kozaka T., Kitamura Y., Ogawa K., Taki J., Kinuya S. and Shiba K., In vitro and in vivo evaluation of [(125)/(123)I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([(125)/(123)I]-OI5V) as a potential sigma-1 receptor ligand for SPECT.
Ann Nucl Med, (2021).
DOI: 10.1007/s12149-020-01552-w
Mori H., Taki J., Wakabayashi H., Hiromasa T., Inaki A., Ogawa K., Shiba K. and Kinuya S., Colchicine treatment early after infarction attenuates myocardial inflammatory response demonstrated by (14)C-methionine imaging and subsequent ventricular remodeling by quantitative gated SPECT.
Ann Nucl Med, (2021).
DOI: 10.1007/s12149-020-01559-3
2020年
Effendi N., Mishiro K., Shiba K., Kinuya S. and Ogawa K., Development of Radiogallium-Labeled Peptides for Platelet-Derived Growth Factor Receptor β (PDGFRβ) Imaging: Influence of Different Linkers.
Molecules, 26, 41, (2020).
DOI: 10.3390/molecules26010041
Ho T. T. B., Nasti A., Seki A., Komura T., Inui H., Kozaka T., Kitamura Y., Shiba K., Yamashita T., Yamashita T., Mizukoshi E., Kawaguchi K., Wada T., Honda M., Kaneko S. and Sakai Y., Combination of emcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis.
J Immunother Cancer, 8, (2020).
DOI: 10.1136/jitc-2020-001367
Kikuchi A., Takayama H., Tsugane H., Shiba K., Chikamoto K., Yamamoto T., Matsugo S., Ishii K.-a., Misu H. and Takamura T., Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in mice.
Scientific Reports, 10, 13260, (2020).
DOI: 10.1038/s41598-020-70192-x
Ogawa K., Higashi T., Mishiro K., Wakabayashi H., Shiba K., Odani A. and Kinuya S., Decreasing undesirable absorbed radiation to the intestine after administration of radium-223 dichloride for treatment of bone metastases.
Sci Rep, 10, 11917, (2020).
DOI: 10.1038/s41598-020-68846-x
Fawwaz M., Mishiro K., Nishii R., Sawazaki I., Shiba K., Kinuya S. and Ogawa K., Synthesis and Fundamental Evaluation of Radioiodinated Rociletinib (CO-1686) as a Probe to Lung Cancer with L858R/T790M Mutations of Epidermal Growth Factor Receptor (EGFR).
Molecules, 25, 2914, (2020).
DOI: 10.3390/molecules25122914
Miwa D., Kitamura Y., Kozaka T., Shigeno T., Ogawa K., Taki J., Kinuya S. and Shiba K., (-)-o-[(11)C]methyl-trans-decalinvesamicol ((-)-[(11)C]OMDV) as a PET ligand for the vesicular acetylcholine transporter.
Synapse, 74, e22176, (2020).
DOI: 10.1002/syn.22176
Hiromasa T., Taki J. i., Wakabayashi H., Inaki A., Okuda K., Shibutani T., Shiba K. and Kinuya S., Serial examination of cardiac function and perfusion in growing rats using SPECT/CT for small animals.
Scientific Reports, 10, 160, (2020).
DOI: 10.1038/s41598-019-57032-3
2019年
Wakabayashi H., Taki J., Inaki A., Hiromasa T., Yamase T., Akatani N., Okuda K., Shibutani T., Shiba K. and Kinuya S., Prognostic Value of Early Evaluation of Left Ventricular Dyssynchrony After Myocardial Infarction.
Mol Imaging Biol, 21, 654-659, (2019).
DOI: 10.1007/s11307-018-1279-7
Ishizaki A., Mishiro K., Shiba K., Hanaoka H., Kinuya S., Odani A. and Ogawa K., Fundamental study of radiogallium-labeled aspartic acid peptides introducing octreotate derivatives.
Annals of Nuclear Medicine, 33, 244-251, (2019).
DOI: 10.1007/s12149-018-01326-5
Effendi N., Mishiro K., Takarada T., Yamada D., Nishii R., Shiba K., Kinuya S., Odani A. and Ogawa K., Design, synthesis, and biological evaluation of radioiodinated benzo[d] imidazole-quinoline derivatives for platelet-derived growth factor receptor beta (PDGFR beta) imaging.
Bioorganic & Medicinal Chemistry, 27, 383-393, (2019).
DOI: 10.1016/j.bmc.2018.12.016
Ogawa K., Masuda R., Mishiro K., Wang M., Kozaka T., Shiba K., Kinuya S. and Odani A., Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging.
Bioorganic & Medicinal Chemistry, 27, 1990-1996, (2019).
DOI: 10.1016/j.bmc.2019.03.054
Ogawa K., Takeda T., Mishiro K., Toyoshima A., Shiba K., Yoshimura T., Shinohara A., Kinuya S. and Odani A., Radiotheranostics Coupled between an At-211-Labeled RGD Peptide and the Corresponding Radioiodine-Labeled RGD Peptide.
ACS Omega, 4, 4584-4591, (2019).
DOI: 10.1021/acsomega.8b03679
Taki J., Inaki A., Wakabayashi H., Matsunari I., Imanaka-Yoshida K., Ogawa K., Hiroe M., Shiba K. and Kinuya S., Postconditioning Accelerates Myocardial Inflammatory Resolution Demonstrated by (14)C-Methionine Imaging and Attenuates Ventricular Remodeling After Ischemia and Reperfusion.
Circ J, 83, 2520-2526, (2019).
DOI: 10.1253/circj.CJ-19-0462
2018年
Ogawa K., Takeda T., Yokokawa M., Yu J., Makino A., Kiyono Y., Shiba K., Kinuya S. and Odani A., Comparison of Radioiodine- or Radiobromine-Labeled RGD Peptides between Direct and Indirect Labeling Methods.
Chem Pharm Bull (Tokyo), 66, 651-659, (2018).
DOI: 10.1248/cpb.c18-00081
Ogawa K., Masuda R., Mizuno Y., Makino A., Kozaka T., Kitamura Y., Kiyono Y., Shiba K. and Odani A., Development of a novel radiobromine-labeled sigma-1 receptor imaging probe.
Nucl Med Biol, 61, 28-35, (2018).
DOI: 10.1016/j.nucmedbio.2018.03.005
Effendi N., Mishiro K., Takarada T., Makino A., Yamada D., Kitamura Y., Shiba K., Kiyono Y., Odani A. and Ogawa K., Radiobrominated benzimidazole-quinoline derivatives as Platelet-derived growth factor receptor beta (PDGFRβ) imaging probes.
Scientific Reports, 8, 10369, (2018).
DOI: 10.1038/s41598-018-28529-0
Wakabayashi H., Taki J., Inaki A., Hiromasa T., Okuda K., Shibutani T., Shiba K. and Kinuya S., Quantification of Myocardial Perfusion Defect Size in Rats: Comparison between Quantitative Perfusion SPECT and Autoradiography.
Mol Imaging Biol, 20, 544-550, (2018).
DOI: 10.1007/s11307-018-1159-1
総説
Ogawa K and Shiba K*. In vivo and in vitro characteristics of radiolabeled vesamicol analogs as the Vesicular Acetylcholine Transporter (VAChT) imaging agents.
Contrast Media & Molecular Imaging, Article ID 4535476, 14 pages, (2018).
DOI: https://doi.org/10.1155/2018/4535476
著書
柴 和弘（WG委員長）：「法令改正に伴う放射線障害予防規程の変更のための作成マニュアル」（大学等放射線施設協議会）2018年7月25日
大学等施設協議会HPに掲載
2017年
Shigeno T., Kozaka T., Kitamura Y., Ogawa K. and Shiba K., Characteristics of 2-[4-(2-iodophenyl)piperidino]cyclopenntanon (OI5V) as a new siguma-1 receptor imaging agent.
Journal of Nuclear Medicine, 58, 865, (2017).
Oshima N., Akizawa H., Kawashima H., Zhao S., Zhao Y., Nishijima K.-i., Kitamura Y., Arano Y., Kuge Y. and Ohkura K., Redesign of negatively charged
111In-DTPA-octreotide derivative to reduce renal radioactivity.
Nuclear Medicine and Biology, 48, 16-25, (2017).
DOI: 10.1016/j.nucmedbio.2017.01.006
Oshima N., Akizawa H., Kawashima H., Zhao S., Zhao Y., Nishijima K. I., Kitamura Y., Arano Y., Kuge Y. and Ohkura K., Redesign of negatively charged 111In-DTPA-octreotide derivative to reduce renal radioactivity.
Nucl Med Biol, 48, 16-25, (2017).
DOI: 10.1016/j.nucmedbio.2017.01.006
Ogawa K., Ishizaki A., Takai K., Kitamura Y., Makino A., Kozaka T., Kiyono Y., Shiba K. and Odani A., Evaluation of Ga-DOTA-(D-Asp)n as bone imaging agents: D-aspartic acid peptides as carriers to bone.
Scientific Reports, 7, 13971, (2017).
DOI: 10.1038/s41598-017-14149-7
Effendi N., Ogawa K., Mishiro K., Takarada T., Yamada D., Kitamura Y., Shiba K., Maeda T. and Odani A., Synthesis and evaluation of radioiodinated 1-{2-[5-(2-methoxyethoxy)-1H-benzo[d]imidazol-1-yl]quinolin-8-yl}piperidin-4-amine derivatives for platelet-derived growth factor receptor β (PDGFRβ) imaging.
Bioorganic Medicinal Chemistry, 25, 5576-5585, (2017).
DOI: https://doi.org/10.1016/j.bmc.2017.08.025
総説
gawa K., Masuda R. and Shiba K., Development of radiolabeled probes directed against sigma-1 receptors.
Bunseki Kagaku (Japan Analyst), 66, 403-411, (2017).
DOI:https://doi.org/10.2116/bunsekikagaku.66.403
2016年
Ogawa K, Fukuda T, Han J, Kitamura Y, Shiba K, and Odani A. Evaluation of Chlorella as a decorporation agent to enhance the elimination of radioactive strontium from body.
PLoS One(2016).
DOI: 10.1371/journal.pone.0148080.
Kobayashi M, Matsunari I, Nishi K, Mizutani A, Miyazaki Y, Ogai K, Sugama J, Shiba K, Kawai K, Kinuya S. Simultaneous acquisition of 99mTc and 123I-labeled radiotracers using a preclinical SPECT scanner with CZT detector.
Ann Nucl Med.,30, 263-271.(2016)
DOI：10.1007/s12149-015-1055-6
Kitamura Y, Kozaka T, Miwa D, Uno I, Azim MA, Ogawa K, Taki J, Kinuya S and Shiba K. Synthesis and evaluation of a new vesamicol analog o-[11C]methyl-trans-decalinvesamicol as a PET ligand for the vesicular acetylcholine transporter.
Ann. Nucl. Med.,30,122-129,(2016).
DOI 10.1007/s12149-015-1039-6.
Uno I, Kozaka T, Miwa D, Kitamura Y, Azim MA, Ogawa K, Taki J, Kinuya S and Shiba K. In vivo differences between two optical isomers of radioiodinated o-iodo-trans-decalinvesamicol for use as a radioligand for the vesicular acetylcholine transporter.
PLOS ONE, (2016)
DOI:10.1371/journal.pone.014671
Kobayashi M., Matsunari I., Nishi K., Mizutani A., Miyazaki Y., Ogai K., Sugama J., Shiba K., Kawai K. and Kinuya S., Simultaneous acquisition of (99m)Tc- and (123)I-labeled radiotracers using a preclinical SPECT scanner with CZT detectors.
Ann Nucl Med, 30, 263-271, (2016).
DOI: 10.1007/s12149-015-1055-6
著書
柴 和弘（編集委員長）：大学等における申請書等の作製マニュアル 2016年版
（大学等放射線施設協議会「大学等における申請書等の作製マニュアル」編集委員会 編集）
第1章 放射線障害防止法関係法の改正の概要 5-13頁
第3章 非密封線源使用施設 23-111頁
株式会社 アドスリー、 東京、2016.5.31(発行)
2015年
Wakabayashi H, Taki J, Inaki A, Shiba K, Matsunari I and Kinuya S. Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion.
EJNMMI Res. ,5(1), 72, pp 1-6, (2015).
DOI 10.1186/s13550-015-0152-9.
Taki J., Inaki A., Wakabayashi H., Matsunari I., Imanaka-Yoshida K., Ogawa K., Hiroe M., Shiba K., Yoshida T. and Kinuya S., Effect of postconditioning on dynamic expression of tenascin-C and left ventricular remodeling after myocardial ischemia and reperfusion.
EJNMMI Res., 5, 21, (2015).
Ogawa K., Yu J., Ishizaki A., Yokokawa M., Kitamura M., Kitamura Y., Shiba K. and Odani A., Radiogallium Complex-Conjugated Bifunctional Peptides for Detecting Primary Cancer and Bone Metastases Simultaneously.
Bioconjugate Chemistry, 26, 1561-1570, (2015).
Ogawa K., Mizuno Y., Washiyama K., Shiba K., Takahashi N., Kozaka T., Watanabe S., Shinohara A. and Odani A., Preparation and evaluation of an astatine-211-labeled sigma receptor ligand for alpha radionuclide therapy.
Nucl Med Biol, 42, 875-879, (2015).
総説
小阪孝史、北村陽二、柴 和弘：脳内小胞アセチルコリントランスポーターのイメージング研究 PET journal 2015, Volume 29, Spring 2015, pp. 8-11.
その他出版物
柴 和弘：「大学における放射線教育」 岡山大学 自然生命科学研究支援センター 鹿田施設ニュース 巻頭言 2015年8月
2014年
Oshima N., Akizawa H., Zhao S., Zhao Y., Nishijima K., Kitamura Y., Arano Y., Kuge Y. and Ohkura K., Design, synthesis and biological evaluation of negatively charged (1)(1)(1)In-DTPA-octreotide derivatives.
Bioorg Med Chem, 22, 1377-1382, (2014).
Lopatina O., Yoshihara T., Nishimura T., Zhong J., Akther S., Fakhrul A. A., Liang M., Higashida C., Sumi K., Furuhara K., Inahata Y., Huang J. J., Koizumi K., Yokoyama S., Tsuji T., Petugina Y., Sumarokov A., Salmina A. B., Hashida K., Kitao Y., Hori O., Asano M., Kitamura Y., Kozaka T., Shiba K., Zhong F., Xie M. J., Sato M., Ishihara K. and Higashida H., Anxiety- and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson's disease.
Front Behav Neurosci, 8, 133, (2014).
Kozaka T., Uno I., Kitamura Y., Miwa D., Anwar-Ul Azim M., Ogawa K. and Shiba K., Regional brain imaging of vesicular acetylcholine transporter using o-[125I]iodo-trans-decalinvesamicol as a new potential imaging probe.
Synapse, 68, 107-113, (2014).
Azim M. A.-u., Kozaka T., Uno I., Miwa D., Kitamura Y., Ogawa K., Makino A., Kiyono Y. and Shiba K., The potential of o-bromo-trans-decalinvesamicol as a new PET ligand for vesicular acetylcholine transporter imaging.
Synapse, 68, 445-453, (2014).
2013年
Ogawa K., Ishizaki A., Takai K., Kitamura Y., Kiwada T., Shiba K. and Odani A., Development of Novel Radiogallium-Labeled Bone Imaging Agents Using Oligo-Aspartic Acid Peptides as Carriers.
PLoS ONE,
8, e84335, (2013).
Shiba K., Kitamura Y., Kozaka T., Uno I., Shimizu K., Masumoto K., Hirota M., Higaki S., Miyoshi H., Saze T., Sakama M., Yanaga M.,Decontamination of radioactivity from contaminated vegetables derived from The Fukushima nuclear accident.
Radiation Measurements, 55, 26-29 (2013).
Kadowaki S., Munekane M., Kitamura Y., Hiromura M., Kamino S., Yoshikawa Y., Saji H., Enomoto S., Development of new zinc dithiosemicarbazone complex for use as oral antidiabetic agent.
Biological Trace Element Research, 154, 111-119 (2013).
Ogawa K., Ohtsuki K., Shibata T., Aoki M., Nakayama M., Kitamura Y., Ono M., Ueda M., Doue T., Onoguchi M., Shiba K. and Odani A., Development and Evaluation of a Novel
99mTc-Labeled Annexin A5 for Early Detection of Response to Chemotherapy.
PLoS ONE, 8, e81191, (2013).
Shiba K., Report regarding radioactivity removal from contaminated vegetables derived from the Fukushima nuclear accident.
Radiation Safety Management, 12(1), 31-36 (2013).
Ogawa K., Kanbara H., Kiyono Y., Kitamura Y., Kiwada T., Kozaka T., Kitamura M., Mori T., Shiba K., Odani A., Development and evaluation of a radiobromine-labeled sigma ligand for
tumor imaging.
Nuclear Medicine and Biology, 40, 445-450 (2013).
Taki J., Wakabayashi H., Inaki A., Imanaka-Yoshida K., Hiroe M., Ogawa K., Morooka M., Kubota K., Shiba K., Yoshida T. and Kinuya S., 14C-Methionine Uptake as a Potential Marker of Inflammatory Processes After Myocardial Ischemia and Reperfusion.
Journal of Nuclear Medicine, 54, 431-436 (2013).
著書
柴 和弘（分担執筆）：核医学テキスト（絹谷清剛 編集）放射性医薬品、15-23頁、株式会社 中外医学社、東京、2013.4.15 (発行)
2012年
Shiba K., Kitamura Y., Kozaka T., Uno I., Shimizu K., Hirota M., Higaki S. and Masumoto K., Characteristics of radioactive contamination of vegetables derived
from the Fukushima nuclear accident.
Radiation Safety Management, 11(1),19-22 (2012).
Shiba K., Kitamura Y., Kozaka T., Uno I., Miyoshi H., Yanaga M., Chemical removal of radionuclides in contaminated spinach derived from
the Fukushima nuclear accident.
Radiation Safety Management, 11(1), 23-26 (2012).
Ogawa K., Kanbara H., Shiba K., Kitamura Y., Kozaka T., Kiwada T. and Odani A., Development and evaluation of a novel radioiodinated vesamicol analog as a sigma receptor imaging agent.
EJNMMI Research, 2, 54-63 (2012).
柴 和弘：放射線による健康影響―福島第一原発事故の放射能汚染とその影響― CAMPUS HEALTH 49(2) 特集号 特集：東日本大震災と大学 March, 2012. 49 (2), 141-146. 3月
Kozaka T., Uno I., Kitamura Y., Miwa D., Ogawa K., Shiba K., Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT).
Bioorg Med Chem., 20(16), 4936-4941 (2012).
Sugihara T., Munesue S., Yamamoto Y., Sakurai S., Akhter N., Kitamura Y., Shiba K., Watanabe T., Yonekura H., Hayashi Y., Hamada J. and Yamamoto H., Endogenous Secretory Receptor for Advanced Glycation End-Products Inhibits Amyloid-beta(1-42) Uptake into Mouse Brain.
Journal of Alzheimers Disease, 28, 709-720 (2012).
その他出版物
柴 和弘：「放射線被ばくとこころの影響」 東京大学アイソトープ総合センターニュース 巻頭言 43(3) 2012. 12月25日
2011年
Nakagawa-Goto K., Wu P. C., Lai C. Y., Hamel E., Zhu H., Zhang L., Kozaka T., Ohkoshi E., Goto M., Bastow K. F. and Lee K. H., Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents.
J Med Chem, 54, 1244-1255 (2011).
Ogawa K., Takai K., Kanbara H., Kiwada T., Kitamura Y., Shiba K. and Odani A., Preparation and evaluation of a radiogallium complex-conjugated bisphosphonate as a bone scintigraphy agent.
Nuclear Medicine and Biology, 38, 631-636 (2011).
柴 和弘, 福島第一原発事故によって汚染された野菜に付着した放射性物質の除去法に関する中間報告.
日本放射線安全管理学会誌, 2, 110-112 (2011).
柴 和弘，西澤邦秀, 福島第一原発事故によって汚染された野菜に付着した放射性物質の除去法に関する報告.
日本放射線安全管理学会誌, 2, 135-151 (2011).
柴 和弘, 福島原発事故で汚染した野菜はどれくらい放射能除去できるのか？.
ATOMOΣ, 53, 817-820 (2011).
柴 和弘：福島第一原発事故によって汚染された野菜に付着した放射性物質の除去法に関する中間報告,ISOTOPE NEWS,No.689, 9 (Sep. 11): 55-58 (2011).
2010年
Kozaka T., Nakagawa-Goto K., Shi Q., Lai C. Y., Hamel E., Bastow K. F., Brossi A. and Lee K. H., Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agents.
Bioorg Med Chem Lett, 20, 4091-4094 (2010).
Taki J., Inaki A., Wakabayashi H., Imanaka-Yoshida K., Ogawa K., Hiroe M., Shiba K., Yoshida T. and Kinuya S., Dynamic expression of tenascin-C after myocardial ischemia and reperfusion: assessment by 125I-anti-tenascin-C antibody imaging.
J Nucl Med, 51, 1116-1122 (2010).
Ogawa K., Takai K., Kiwada T., Kitamura Y., Shiba K. and Odani A., Development and evaluation of a novel radiogallium labeled peptide as a bone imaging agent for PET.
Abstracts of Papers of the American Chemical Society, 240, (2010).
2009年
Shiba K., Torashima T., Hirai H., Ogawa K., Akhter N., Nakajima K., Kinuya S. and Mori H., Potential usefulness of D2R reporter gene imaging by IBF as gene therapy monitoring for cerebellar neurodegenerative diseases.
J Cereb Blood Flow Metab, 29, 434-440 (2009).
Shiba K., Nishiyama S., Tsukada H., Ishiwata K., Kawamura K., Ogawa K. and Mori H., The potential of (-)-o-[11C]methylvesamicol for diagnosing cholinergic deficit dementia.
Synapse, 63, 167-171 (2009).
Ogawa K., Shiba K., Akhter N., Yoshimoto M., Washiyama K., Kinuya S., Kawai K. and Mori H., Evaluation of radioiodinated vesamicol analogs for sigma receptor imaging in tumor and radionuclide receptor therapy.
Cancer Science, 100, 2188-2192 (2009).
Ogawa K., Mukai T., Kawai K., Takamura N., Hanaoka H., Hashimoto K., Shiba K., Mori H. and Saji H., Usefulness of competitive inhibitors of protein binding for improving the pharmacokinetics of (186)Re-MAG3-conjugated bisphosphonate ((186)Re-MAG3-HBP), an agent for treatment of painful bone metastases.
European Journal of Nuclear Medicine and Molecular Imaging, 36, 115-121 (2009).
Ogawa K., Kawashima H., Shiba K., Washiyama K., Yoshimoto M., Kiyono Y., Ueda M., Mori H. and Saji H., Development of [(90)Y]DOTA-conjugated bisphosphonate for treatment of painful bone metastases.
Nuclear Medicine and Biology, 36, 129-135 (2009).
Ogawa K., Kawashima H., Kinuya S., Shiba K., Onoguchi M., Kimura H., Hashimoto K., Odani A. and Saji H., Preparation and evaluation of 186/188Re-labeled antibody (A7) for radioimmunotherapy with rhenium(I) tricarbonyl core as a chelate site.
Ann Nucl Med, 23, 843-848 (2009).
Ogawa K., Akhter N. and Shiba K., BIODISTRIBUTION AND METABOLIC STUDIES OF A RADIOIODINATED VESAMICOL ANOLOG AS A SIGMA RECEPTOR LIGAND FOR TUMOR IMAGING.
Journal of Labelled Compounds & Radiopharmaceuticals, 52, S359-S359 (2009).
2008年
Yoshimoto M., Ogawa K., Washiyama K., Shikano N., Mori H., Amano R. and Kawai K., alpha(v)beta(3) Integrin-targeting radionuclide therapy and imaging with monomeric RGD peptide.
Int J Cancer, 123, 709-715 (2008).
Ueda M., Iida Y., Kitamura Y., Kawashima H., Ogawa M., Magata Y. and Saji H., 5-Iodo-A-85380, a specific ligand for alpha4beta2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicity in rat cortical cultured neurons.
Brain Res, 1199, 46-52 (2008).
Kitamura Y., Mori K., Yamamoto M., Nozaki A., Saito M., Tsukamoto I., Mifune M. and Saito Y., Peroxidase-like catalytic activity of aqueous- and immobilized-Mn3+-octabromo- porphyrins on ion-exchange resin supplied as mimetic of horseradish peroxidase., Chemical & Pharmaceutical Bulletin, 56, 1364-1366 (2008).
Kitamura Y., Mifune M., Takatsuki T., Iwasaki T., Kawamoto M., Iwado A., Chikuma M. and Saito Y., Ion-exchange resins modified with metal-porphyrin as a catalysis for oxidation of epinephrine (adrenaline).
Catalysis Communications, 9, 224-228 (2008).
Kawashima H., Ogawa K., Kinuya S., Shiba K., Kimura H., Hashimato K., Mori H. and Saji H., Synthesis and in vivo evaluation of (188)Re-labeled antibody using rhenium(I) tricarbonyl complex.
Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 128, 53-53 (2008).
Doue T., Ohtsuki K., Ogawa K., Ueda M., Azuma A., Saji H., Strauss H. W. and Matsubara H., Cardioprotective effects of erythropoietin in rats subjected to ischemia-reperfusion injury: assessment of infarct size with 99mTc-annexin V.
J Nucl Med, 49, 1694-1700 (2008).
Akhter N., Shiba K., Ogawa K., Tsuji S., Kinuya S., Nakajima K. and Mori H., A change of in vivo characteristics depending on specific activity of radioiodinated (+)-2-[4-(4-iodophenyl)piperidino]cyclohexanol [(+)-pIV] as a ligand for sigma receptor imaging.
Nucl Med Biol, 35, 29-34 (2008).
2007年
van Waarde A., Shiba K., de Jong J. R., Ishiwata K., Dierckx R. A. and Elsinga P. H., Rapid reduction of sigma(1)-Receptor binding and F-18-FDG uptake in rat gliomas after in vivo treatment with doxorubicin.
Journal of Nuclear Medicine, 48, 1320-1326 (2007).
Saji H., Ogawa K., Kitamura Y., Kubota-Akizawa M. and Kawashima H., Chemical Control of Biological Activity and Biodistribution of Metal Compounds: Drug Design of Metal Complexes with Biological Activity and Target-Specific Biodistribution.
Biomed Res Trace Elements, 18, 255-263 (2007).
Ogawa K., Mukai T., Asano D., Kawashima H., Kinuya S., Shiba K., Hashimoto K., Mori H. and Saji H., Therapeutic effects of a 186Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model.
J Nucl Med, 48, 122-127 (2007).
Ogawa K., Kawashima H., Kinuya S., Yoshimoto M., Shiba K., Kimura H., Hashimoto K., Mori H. and Saji H., Preparation of Re-188-labeled antibody (A7) by a simple method using rhenium (I) tricarbonyl complex.
European Journal of Nuclear Medicine and Molecular Imaging, 34, S334-S334 (2007).
Mifune M., Kamiguchi H., Tai T., Kuremoto S., Yamamoto M., Tsukamoto I., Saito M., Kitamura Y. and Saito Y., Peroxidase-like catalytic activity of Mn3+-octabromo-tetrakis(4-sulfophenyl)porphine on linoleate hydroperoxide and its analytical application.
Talanta, 71, 456-461 (2007).
Kozaka T., Miyakoshi N. and Mukai C., Stereoselective total syntheses of three Lycopodium alkaloids, (-)-magellanine, (+)-magellaninone, and (+)-paniculatine, based on two Pauson-Khand reactions.
Journal of Organic Chemistry, 72, 10147-10154 (2007).
Kitamura Y., Takatsuki T., Kawamoto M., Saito M., Iwado A., Tsukamoto I., Mifune M. and Saito Y., Catalytic activity of silica gels bound manganese(III)-porphyrin on oxidative reaction of adrenaline.
Chem Pharm Bull 55, 500-502 (2007).
Kinuya S., Yokoyama K., Fukuoka M., Hiramatsu T., Mori H., Shiba K., Watanabe N., Shuke N., Michigishi T. and Tonami N., Intraperitoneal radioimmunotherapy to treat the early phase of peritoneal dissemination of human colon cancer cells in a murine model.
Nucl Med Commun, 28, 129-133 (2007).
Kawamura K., Tsukada H., Shiba K., Tsuji C., Harada N., Kimura Y. and Ishlwata K., Synthesis and evaluation of fluorine-18-labeled SA4503 as a selective sigma(1) receptor ligand for positron emission tomography.
Nuclear Medicine and Biology, 34, 571-577 (2007).
Akizawa H., Saito M., Tsukamoto I., Ohkura T., Shimizu T., Kitamura Y., Mifune M., Saito Y., Arano Y. and Saji H., Effect of Carboxyl-Group of D-Glutamic Acid or gamma-Carboxy-D-glutamic Acid as N-Terminal Amino Acid of (111)In-Diethylenetriaminepentaacetic Acid-Octreotide on Accumulation of Radioactivity in Kidney.
Biol Pharm Bull, 30, 2226-2228 (2007).
Akhter N., Shiba K., Ogawa K., Kinuya S., Nakajima K. and Mori H., In vivo characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino] cyclohexanol as a potential sigma-1 receptor imaging agent.
Nucl Med Biol, 34, 697-702 (2007).
2006年
Tsukamoto I., Saito M., Yamane M., Kawata K., Kitamura Y., Kitamura Y., Mifune M., Saito Y. and Haginaka J., HPLC retention behaviors of pi-electron rich compounds on Ni2+- and Cu2+-phthalocyanine derivatives bound to silica gels in polar eluents.
Anal Sci, 22, 1035-1038 (2006).
Shiba K., Ogawa K., Kinuya S., Yajima K. and Mori H., A simple and rapid radiochemical choline acetyltransferase (ChAT) assay screening test.
J Neurosci Methods, 157, 98-102 (2006).
Shiba K., Ogawa K., Ishiwata K., Yajima K. and Mori H., Synthesis and binding affinities of methylvesamicol analogs for the acetylcholine transporter and sigma receptor.
Bioorg Med Chem, 14, 2620-2626 (2006).
Mifune M., Kawata K., Tanaka K., Kitamura Y., Tsukamoto I., Saito M., Haginaka J. and Saito Y., HPLC retention behaviors of poly-aromatic-hydrocarbones on Cu(II)-octabromotetrakis(4-carboxyphenyl)porphine derivatives-immobilized aminopropyl silica gels in polar and non-polar eluents.
Chem Pharm Bull 54, 94-98 (2006).
Mifune M., Iwasaki T., Kozaki Y., Tsukamoto I., Saito M., Kitamura Y., Yamaguchi T. and Saito Y., Evaluation of the state of active ingredients in pharmaceutical preparations using fourier transform-Raman difference spectra.
Yakugaku Zasshi, 126, 1363-1367 (2006).
Kitamura Y., Mifune M., Hino D., Yokotani S., Saito M., Tsukamoto I., Iwado A. and Saito Y., Peroxidase-like catalytic activity of Mn- and Fe-tetrakis(4-carboxyphenyl)porphines bound to aminopropyl-glass bead in oxidative reaction of heterocyclic amines.
Talanta, 69, 43-47 (2006).
Kitamura Y., Kawata K., Tanaka K., Furuyashiki Y., Mifune M., Tsukamoto I., Saito M., Haginaka J. and Saito Y., Effect of octabromination of a tetrakis(4-carboxyphenyl)porphine derivative bound to silica gels on HPLC retention behaviors of polyaromatic hydrocarbons.
Talanta, 69, 1260-1264 (2006).
Kitamura Y., Iwasaki T., Saito M., Mifune M., Saito Y., Sato K., Yomota C. and Tanamoto K., Standard Infrared Absorption Spectrum of Betaine and Optimal Conditions for its Measurement J.
Food Hygienics Society of Japan, 47, 232-236 (2006).
Kitamura Y., Iida Y., Abe J., Ueda M., Mifune M., Kasuya F., Ohta M., Igarashi K., Saito Y. and Saji H., Protective effect of zinc against ischemic neuronal injury in a middle cerebral artery occlusion model.
J Pharmacol Sci, 100, 142-148 (2006).
Kitamura Y., Iida Y., Abe J., Mifune M., Kasuya F., Ohta M., Igarashi K., Saito Y. and Saji H., In vivo measurement of presynaptic Zn2+ release during forebrain ischemia in rats.
Biol Pharm Bull, 29, 821-823 (2006).
Kitamura Y., Iida Y., Abe J., Mifune M., Kasuya F., Ohta M., Igarashi K., Saito Y. and Saji H., Release of vesicular Zn(2+) in a rat transient middle cerebral artery occlusion model.
Brain Res Bull, 69, 622-625 (2006).
Kinuya S., Bai J., Shiba K., Yokoyama K., Mori H., Fukuoka M., Watanabe N., Shuke N., Michigishi T. and Tonami N., 99mTc-sestamibi to monitor treatment with antisense oligodeoxynucleotide complementary to MRP mRNA in human breast cancer cells.
Ann Nucl Med, 20, 29-34 (2006).
Kawamura K., Shiba K., Tsukada H., Nishiyama S., Mori H. and Ishiwata K., Synthesis and evaluation of vesamicol analog (-)-O-[11C]methylvesamicol as a PET ligand for vesicular acetylcholine transporter.
Ann Nucl Med, 20, 417-424 (2006).
Ishiwata K., Kawamura K., Yajima K., QingGeLeTu, Mori H. and Shiba K., Evaluation of (+)-p-[11C]methylvesamicol for mapping sigma1 receptors: a comparison with [11C]SA4503.
Nucl Med Biol, 33, 543-548 (2006).
Bai J., Kinuya S., Shiba K., Michigishi T. and Tonami N., Binding with serum components favorably affects cellular uptake of 111In-oligonucleotide in a leukemia cell line.
Cancer Biother Radiopharm, 21, 34-40 (2006).
Nishie T., Renhua, Ogawa K., Shiba K., Mori H., Wada T. and Asano M., Analysis of molecular mechanisms of IgA nephropathy in β-1,4-galactosyltransferase-I-deficient mice.
Nephrology, 11, A68 (2006).
Kinuya S., Bai J., Yokoyama K., Shiba K., Mori H., Fukuoka M., Watanabe N., Shuke N., Michigishi T. and Tonami N., Changes of Tc-99m sestamibi uptake in P-glycoprotein expressing leukaemia Cells Treated in vivo with antisense oligodeoxynucleotide Complementary to mdr1 mRNA.
World Journal of Nuclear Medicine, 5, 115-118 (2006).
2005年
Shiba K., Ogawa K. and Mori H., In vitro characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino]cyclohexanol [(+)-pIV] as a sigma-1 receptor ligand.
Bioorg Med Chem, 13, 1095-1099 (2005).
Mifune M., Hino D., Sugita H., Iwado A., Kitamura Y., Motohashi N., Tsukamoto I. and Saito Y., Peroxidase-like catalytic activity of anion-exchange resins modified with metal-porphyrins in oxidative reaction of hetrocyclic amines with hydrogen peroxide.
Chem Pharm Bull, 53, 1006-1010. (2005).
Kinuya S., Yokoyama K., Izumo M., Sorita T., Obata T., Mori H., Shiba K., Watanabe N., Shuke N., Michigishi T. and Tonami N., Locoreginal radioimmunotherapy with 186Re-labeled monoclonal antibody in treating small peritoneal carcinomatosis of colon cancer in mice in comparison with 131I-counterpart.
Cancer Lett, 219, 41-48 (2005).
Kinuya S., Yokoyama K., Fukuoka M., Mori H., Shiba K., Watanabe N., Shuke N., Michigishi T. and Tonami N., Anti-angiogenic therapy and chemotherapy affect 99mTc sestamibi and 99mTc-HL91 accumulation differently in tumour xenografts.
Nucl Med Commun, 26, 1067-1073 (2005).
Kawamura K., Shiba K., Yajima K. and Ishiwata K., SYNTHESIS AND EVALUATION OF (11)C-LABELED METHYLVESAMICOLS AS A PET LIGAND FOR VESICULAR ACETYLCHOLINE TRANSPORTERS OR SIGMA RECEPTORS.
Journal of Labelled Compounds & Radiopharmaceuticals, 48, S80-S80 (2005).
2004年
Mukai C., Kozaka T., Suzuki Y. and Kim I. J., New entry to the Pauson-Khand reaction: trimethylgermyl group at the triple bond terminus as a latent functional group.
Tetrahedron, 60, 2497-2507 (2004).
Kiyono Y., Kanegawa N., Kawashima H., Kitamura Y., Iida Y. and Saji H., Evaluation of radioiodinated (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine as a ligand for brain norepinephrine transporter imaging.
Nucl Med Biol, 31, 147-153. (2004).
Kinuya S., Yokoyama K., Koshida K., Mori H., Shiba K., Watanabe N., Shuke N., Bai J., Michigishi T. and Tonami N., Improved survival of mice bearing liver metastases of colon cancer cells treated with a combination of radioimmunotherapy and antiangiogenic therapy.
Eur J Nucl Med Mol Imaging, 31, 981-985 (2004).
Kinuya S., Li X. F., Yokoyama K., Mori H., Shiba K., Watanabe N., Shuke N., Bunko H., Michigishi T. and Tonami N., Hypoxia as a factor for 67Ga accumulation in tumour cells.
Nucl Med Commun, 25, 49-53 (2004).
Kinuya S., Li X. F., Yokoyama K., Mori H., Shiba K., Watanabe N., Shuke N., Bunko H., Michigishi T. and Tonami N., Limitations of (99m)Tc tetrofosmin in assessing reversal effects of verapamil on the function of multi-drug resistance associated protein 1.
Nucl Med Commun, 25, 585-589 (2004).
Kawashima H., Iida Y., Kitamura Y. and Saji H., Binding of 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]pyridinium ion (HPP+), a metabolite of haloperidol, to synthetic melanin: implications for the dopaminergic neurotoxicity of HPP+.
Neurotox Res, 6, 535-542. (2004).
Igarashi K., Murabayashi Y., Hotta K., Kitamura Y., Kasuya F., Shiotani K., Tingyou L., Miyazaki A., Tsuda Y., Okada Y. and Fukushima S., Application of liquid chromatography-tandem mass spectrometry for the determination of opioidmimetics in the brain dialysates from rats treated with opioidmimetics intraperitoneally.
J Chromatogr B Analyt Technol Biomed Life Sci, 806, 53-57. (2004).
Bai J., Yokoyama K., Kinuya S., Shiba K., Matsushita R., Nomura M., Michigishi T. and Tonami N., In vitro detection of mdr1 mRNA in murine leukemia cells with 111In-labeled oligonucleotide.
Eur J Nucl Med Mol Imaging, 31, 1523-1529 (2004).
2003年
Shiba K., Mori H. and Tonami N., Evaluation of radioiodinated (-)-o-iodovesamicol as a radiotracer for mapping the vesicular acetylcholine transporter.
Ann Nucl Med, 17, 451-456 (2003).
Saji H., Iida Y., Kawashima H., Ogawa M., Kitamura Y., Mukai T., Shimazu S. and Yoneda F., In vivo imaging of brain dopaminergic neurotransmission system in small animals with high-resolution single photon emission computed tomography.
Anal Sci, 19, 67-71. (2003).
Kinuya S., Yokoyama K., Izumo M., Sorita T., Obata T., Mori H., Shiba K., Watanabe N., Shuke N., Michigishi T. and Tonami N., Feasibility of 186Re-radioimmunotherapy for treatment in an adjuvant setting of colon cancer.
J Cancer Res Clin Oncol, 129, 392-396 (2003).
Kinuya S., Li X. F., Yokoyama K., Mori H., Shiba K., Watanabe N., Shuke N., Bunko H., Michigishi T. and Tonami N., Local delivery of (131)I-MIBG to treat peritoneal neuroblastoma.
Eur J Nucl Med Mol Imaging, 30, 1246-1250 (2003).
Kinuya S., Li X. F., Yokoyama K., Mori H., Shiba K., Watanabe N., Shuke N., Bunko H., Michigishi T. and Tonami N., Intraperitoneal radioimmunotherapy in treating peritoneal carcinomatosis of colon cancer in mice compared with systemic radioimmunotherapy.
Cancer Sci, 94, 650-654 (2003).
Kinuya S., Li X. F., Yokoyama K., Mori H., Shiba K., Watanabe N., Shuke N., Bunko H., Michigishi T. and Tonami N., Reduction of 99mTc-sestamibi and 99mTc-tetrofosmin uptake in MRP-expressing breast cancer cells under hypoxic conditions is independent of MRP function.
Eur J Nucl Med Mol Imaging, 30, 1529-1531 (2003).
2002年
Shiba K., Yano T., Sato W., Mori H. and Tonami N., Characterization of radioiodinated (-)-ortho-iodovesamicol binding in rat brain preparations.
Life Sci, 71, 1591-1598 (2002).
Saji H., Ogawa M., Ueda M., Iida Y., Magata Y., Tominaga A., Kawashima H., Kitamura Y., Nakagawa M., Kiyono Y. and Mukai T., Evaluation of radioiodinated 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine as a ligand for SPECT investigations of brain nicotinic acetylcholine receptors.
Ann Nucl Med, 16, 189-200. (2002).
Mukai C., Kozaka T., Suzuki Y. and Kim I. J., Trimethylgermyl group in Pauson-Khand reaction.
Tetrahedron Letters, 43, 8575-8578 (2002).
Li X. F., Kinuya S., Yokoyama K., Koshida K., Mori H., Shiba K., Watanabe N., Shuke N., Michigishi T. and Tonami N., Benefits of combined radioimmunotherapy and anti-angiogenic therapy in a liver metastasis model of human colon cancer cells.
Eur J Nucl Med Mol Imaging, 29, 1669-1674 (2002).
Kawashima H., Iida Y., Kitamura Y., Kiyono Y., Magata Y. and Saji H., Brain extraction of 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]pyridinium ion (HPP+), a neurotoxic metabolite of haloperidol: studies using [3H]HPP+.
Jpn J Pharmacol, 89, 426-428. (2002).
2001年
Shiba K., Mori H., Ikeda E., Sumiya H. and Tonami N., The potential of radioiodinated (-)-m-iodovesamicol for diagnosing cholinergic deficit dementia.
Nucl Med Biol, 28, 261-264 (2001).
Ikeda E., Ichikawa A., Mori H., Shiba K., Kuji I., Sumiya H., Tonami N. and Ikeda K., Effect of vagal autotransplantation on quantitative [3H]-vesamicol binding image in rats with unilateral lesions of nucleus baslis magnocellularis.
Neurosci Lett, 300, 33-36 (2001).
2000年
Kubota M., Iida Y., Magata Y., Kitamura Y., Kawashima H. and Saji H., Mechanisms of [2,3-butanedione bis(N4-dimethylthiosemicarbazone)]zinc (Zn-ATSM2)-induced protection of cultured hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
Jpn J Pharmacol, 84, 334-338. (2000).
Ikeda E., Shiba K., Mori H., Ichikawa A., Sumiya H., Kuji I. and Tonami N., Reduction of vesicular acetylcholine transporter in beta-amyloid protein-infused rats with memory impairment.
Nucl Med Commun, 21, 933-937 (2000).
