お問い合わせ

2014年

業績目録

原著

  1. Regulation of 18F-fluorodeoxyglucose accumulation in colorectal cancer cells with mutated KRAS. Masayoshi Iwamoto, Kenji Kawada, Yuji Nakamoto, Yoshiro Itatani, Susumu Inamoto, Kosuke Toda, Hiroyuki Kimura, Takehiko Sasazuki, Senji Shirasawa, Hiroaki Okuyama, Masahiro Inoue, Suguru Hasegawa, Kaori Togashi, Yoshiharu Sakai. Journal of Nuclear Medicine, jnumed.114.142927 (2014)
  2. A 68Ga complex based on benzofuran scaffold for the detection of b-amyloid plaques. Hiroyuki Watanabe, Masahiro Ono, Shimpei Iikuni, Masashi Yoshimura, Kenji Matsumura, Hiroyuki Kimura, Hideo Saji. Bioorganic and Medicinal Chemistry Letters, 24(20), 4834-4837 (2014) 
  3. Development of a resonant-type microwave reactor and its application to the synthesis of positron emission tomography radiopharmaceuticals. Hiroyuki Kimura, Yusuke Yagi, Noriyuki Ohneda, Hiro Odajima, Masahiro Ono, Hideo Saji. Journal of Labelled Compounds and Radiopharmaceuticals, 57(12), 680-686 (2014)
  4. Feasibility of amylin imaging in pancreatic islets with b-amyloid imaging probes. Masashi Yoshimura, Masahiro Ono, Hiroyuki Watanabe, Hiroyuki Kimura, Hideo Saji. Scientific Reports, 4, 6155 (2014)
  5. Gallium-68-labeled anti-HER2 single-chain Fv fragment: Development and In Vivo monitoring of HER2 expression. Masashi Ueda, Hayato Hisada, Takashi Temma, Yoichi Shimizu, Hiroyuki Kimura, Masahiro Ono, Yuji Nakamoto, Kaori Togashi, Hideo Saji. Molecular Imaging and Biology, 17, 102-110 (2014)
  6. Synthesis and evaluation of 18F-labeled mitiglinide derivatives as positron emission tomography tracers for b-cell imaging. Hiroyuki Kimura, Hirokazu Matsuda, Hiroyuki Fujimoto, Kenji Arimitsu, Kentaro Toyoda, Eri Mukai, Hiroshi Nakamura, Yu Ogawa, Mikako Takagi, Masahiro Ono, Nobuya Inagaki, Hideo Saji. Bioorganic & Medicinal Chemistry, 22(13), 3270-3278 (2014)
  7. Enhancement of binding affinity for amyloid aggregates by multivalent interactions of 99mTc-hydroxamamide complexes. Shimpei Iikuni, Masahiro Ono, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Naoya Harada, Hiroyuki Kimura, Morio Nakayama, Hideo Saji. Molecular Pharmaceutics, 11(4), 1132-1139 (2014)
  8. Synthesis and evaluation of a radioiodinated peptide probe targeting avb6 integrin for the detection of pancreatic ductal adenocarcinoma. Masashi Ueda, Takahiro Fukushima, Kei Ogawa, Hiroyuki Kimura, Masahiro Ono, Takashi Yamaguchi, Yuzuru Ikehara, Hideo Saji. Biochemical and Biophysical Research Communications, 445(3), 661-666 (2014)
  9. Smart near-infrared fluorescence probes with donor-acceptor structure for in vivo detection of b-amyloid deposits. Mengchao Cui, Masahiro Ono, Hiroyuki Watanabe, Hiroyuki Kimura, Boli Liu, Hideo Saji. Journal of the American Chemical Society, 136(9), 3388-3394 (2014)
  10. Novel radioiodinated 1,3,4-oxadiazole derivatives with improved in vivo properties for SPECT imaging of b-amyloid plaques. Hiroyuki Watanabe, Masahiro Ono, Hiroyuki Kimura, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hideo Saji. MedChemComm, 5(1), 82-85 (2014)
  11. Synthesis and evaluation of (−)- and (+)-[11C]galanthamine as PET tracers for cerebral acetylcholinesterase imaging. Hiroyuki Kimura,Tomoki Kawai, Yoshio Hamashima, Hidekazu Kawashima, Kenji Miura, Yuta Nakaya, Makoto Hirasawa, Kenji Arimitsu, Tetsuya Kajimoto, Yoshiro Ohmomo, Masahiro Ono, Manabu Node, Hideo Saji. Bioorganic & Medicinal Chemistry, 22(1), 285-291 (2014)
  12. Regional brain imaging of vesicular acetylcholine transporter using o-[125I]iodo-trans-decalinvesamicol as a new potential imaging probe. Takashi Kozaka, Izumi Uno, Yoji Kitamura, Daisuke Miwa, Mohammad Anwar-Ul Azim, Kazuma Ogawa, Kazuhiro Shiba. Synapse, 68, 107-113 (2014), 10.1002/syn.21720.
  13. Anxiety-and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson’s disease. Olga Lopatina, Toru Yoshihara, Tomoko Nishimura, Jing Zhong, Shirin Akther, Azam A K M Fakhrul, Mingkun Liang, Chiharu Higashida, Kohei Sumi, Kazumi Furuhara, Yuki Inahata, Jian-Jung Huang, Keita Koizumi, Shigeru Yokoyama, Takahiro Tsuji, Yulia Petugina, Andrei Sumarokov, Alla B Salmina, Koji Hashida, Yasuko Kitao, Osamu Hori, Masahide Asano, Yoji Kitamura, Takashi Kozaka, Kazuhiro Shiba, Fangfang Zhong, Min-Jue Xie, Makoto Sato, Katsuhiko Ishihara, Haruhiro Higashida. Frontiers in Behavioral Neuroscience, 8, 133/1-133/18, 18 pp. (2014), 10.3389/fnbeh.2014.00133.
  14. The potential of o-bromo-trans-decalinvesamicol as a new PET ligand for vesicular acetylcholine transporter imaging. Mohammad Anwar-Ul Azim, Takashi Kozaka, Izumi Uno, Daisuke Miwa, Yoji Kitamura, Kazuma Ogawa, Akira Makino, Yasushi Kiyono, Kazuhiro Shiba. Synapse, 68, 445-453 (2014), 10.1002/syn.21756.

国際及び国内学会発表

  1. 木村寛之（講演）、豊田健太郎、稲垣暢也、佐治英郎、膵β細胞の定量化を目的としたイメージングプローブの開発、第54回日本核医学会学術総会、（大阪国際会議場）、2014年11月6日～8日
  2. 木村寛之（講演）、膵β細胞の定量化を目指したPET薬剤の開発、PETサマーセミナー2014 in 小樽、（グランドパーク小樽）、2014年8月29日～31日
  3. Hiroyuki Kimura (oral), Yusuke Yagi, Noriyuki Ohneda, Hiro Odajima, Hideo Saji, Development of resonant-type microwave reactor and its application to PET radiochemistry, SNMMI Annual Meeting 2014, ST.Louis, Missouri, June 7-11, 2014
  4. Hiroyuki Kimura (poster), Kaori Kanbe, Hirokazu Matsuda, Kentaro Toyoda, Hiroyuki Fujimoto, Masahiro Ono, Nobuya Inagaki, Hideo Saji, Development of 111In-labeled Exendin-4 derivative for the imaging of GLP-1R receptor expression in pancreatic islets, SNMMI Annual Meeting 2014, ST.Louis, Missouri, June 7-11, 2014

シンポジウム、ワークショップ及び講演

  1. 木村寛之，豊田健太郎，稲垣暢也，佐治英郎．（講演・口頭）：膵β細胞の定量化を目的としたイメージングプローブの開発．第54回日本核医学会学術総会（大阪国際会議場），2014年11月6日～8日
  2. 木村寛之．（講演・口頭）：膵β細胞の定量化を目指したPET薬剤の開発．PETサマーセミナー2014 in 小樽（グランドパーク小樽），2014年8月29日～31日

その他の印刷物(解説、プロシーディング等)

解説

  1. 清野　泰，木村寛之．膵β細胞イメージング, 「胆と膵」, 第35号, 379-384 (2014)
  2. 佐治英郎，上田真史，木村寛之．核医学分子イメージングのための放射性分子プローブの戦的設計, 「PETジャーナル」, 第25号,　17-20 (2014)

プロシーディング

  1. Production of 95mTc for Compton camera. Yuichi Hatsukawa, Kazuyuki Hashimoto, Kazuaki Tsukada, Tetsuya Sato, Masato Asai, Atsushi Toyoshima, Yasuki Nagai, Toru Tanimori, Shinya Sonoda, Shigeto Kabuki, Hideo Saji, Hiroyuki Kimura.Journal of Radioanalytical and Nuclear Chemistry. doi 10.1007/s10967-014-3508-0 (2014)
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