お問い合わせ

2015年

業績目録(木村 寛之)

原著

  1. Structure-activity relationship study of heterocyclic phenylethenyl and pyridinylethenyl derivatives as tau-imaging agents that selectively detect neurofibrillary tangles in Alzheimer’s disease brains. Kenji Matsumura, Masahiro Ono, Ayane Kitada, Hiroyuki Watanabe, Masashi Yoshimura, Shimpei Iikuni, Hiroyuki Kimura, Yoko Okamoto, Masafumi Ihara, Hideo Saji. Journal of Medicinal Chemistry, 58(18), 7241-7257 (2015)
  2. Histological and nuclear medical comparison of inflammation after hemostasis with non-thermal plasma and thermal coagulator. Masashi Ueda, Daiki Yamagami, Keiko Watanabe, Kohei Sano, Hiroyuki Kimura, Hideo Saji, Kenji Ishikawa, Masaru Hori, Hajime Sakakita, Yuzuru Ikehara, Shuichi Enomoto. Plasma Processes and Polymers, 12, 1338-1342 (2015)
  3. Application of microreactor to the preparation of C-11-labeled compounds via O-[11C]methylation with [11C]CH3I: Rapid synthesis of [11C]Raclopride. Hidekazu Kawashima, Hiroyuki Kimura, Yuta Nakaya, Kenji Tomatsu, Kenji Arimitsu, Hiroaki Nakanishi, Eiichi Ozeki, Yuji Kuge, Hideo Saji. Chemical and Pharmaceutical Bulletin, 63(9), 737-740 (2015)
  4. Mechanistic investigation of Anti-Elimination in (Z)-1,2-bis (arylseleno)-1-alkenes and their sulfur analogs. Asami Tarao, Yukako Tabuchi, Eri Sugimoto, Miki Ikeda, Hitomi Uchimoto, Kenji Arimitsu, Hiroyuki Kimura, Ikuo Kawasaki, Masatoshi Kawahata, Kentaro Yamaguchi, Kiyoharu Nishide. Organic & Biomolecular Chemistry, 13, 5964-5971 (2015)
  5. Mechanistic aspects of asymmetric intramolecular Heck reaction involving dynamic kinetic resolution: flexible conformation of the cyclohexenylidene-benzene system. Shinzo Hosoi, Minoru Ozeki, Masashi Nakano, Kenji Arimitsu, Tetsuya Kajimoto, Naoto Kojima, Hiroyuki Iwasaki, Takuya Miura, Hiroyuki Kimura, Manabu Node, Masayuki Yamashita. Tetrahedron, 71, 2317-2326 (2015)
  6. Synthesis and biological evaluation of 123I-labeled pyridyl benzoxazole derivatives: novel b-amyloid imaging probes for single-photon emission computed tomography. Hiroyuki Watanabe, Masahiro Ono, Shimpei Iikuni, Hiroyuki Kimura, Yoko Okamoto, Masafumi Ihara, Hideo Saji. RSC Advances, 5, 1009-1015 (2015)
  7. The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling. Yusuke Yagi, Hiroyuki Kimura*, Kenji Arimitsu, Masahiro Ono, Kazuya Maeda, Hiroyuki Kusuhara, Tetsuya Kajimoto, Yuichi Sugiyama, Hideo Saji. Organic & Biomolecular Chemistry, 13(4), 1113-1121 (2015)
  8. Preparation and evaluation of an astatine-211-labeled sigma receptor ligand for alpha radionuclide therapy. Kazuma Ogawa, Yoshiaki Mizuno, Kohshin Washiyama, Kazuhiro Shiba, Naruto Takahashi, Takashi Kozaka, Shigeki Watanabe, Atsushi Shinohara, Akira Odani. Nuclear Medicine and Biology, 42, 875-879 (2015), 10.1016/j.nucmedbio.2015.07.001.
  9. Radiogallium Complex-Conjugated Bifunctional Peptides for Detecting Primary Cancer and Bone Metastases Simultaneously. Kazuma Ogawa, Jing Yu, Atsushi Ishizaki, Masaru Yokokawa, Masanori Kitamura, Yoji Kitamura, Kazuhiro Shiba, Akira Odani. Bioconjugate Chemistry, 26, 1561-1570 (2015), 10.1021/acs.bioconjchem.5b00186.
  10. 小阪孝史, 北村陽二, 柴 和弘, 「脳内小胞アセチルコリントランスポーターのイメージング研究」, PET journal, Volume 29, pp. 8–11 (2015).

国際及び国内学会発表

  1. Hiroyuki Kimura, Hidekazu Saiki, Yukinori Hasegawa, Yasunori Tokuda, Masahiro Ono, Eiich Ozeki, Yuji Kuge, Ren Iwata, and Hideo Saji. （口頭）One-flow synthesis of N-succinimidyl 4-[18F]fluorobenzoate using a single microfluidic chip. The 2015 International Chemical Congress of Pacific Basin Societies (Hawaii, USA). 2015.12.15-20
  2. Hiroyuki Kimura, Noriyuki Ohneda, Hiro Odajima, Masahiro Ono, and Hideo Saji. （口頭）Development of a continuous flow microwave reactor and its application to the radiochemistry. 21st International Symposium on Radiopharmaceutical Sciences (Columbia, USA). 2015.5.26-31
  3. Hiroyuki Kimura, Hidekazu Saiki, Yukinori Hasegawa, Yasunori Tokuda, Masahiro Ono, Eiich Ozeki, Yuji Kuge, Ren Iwata, and Hideo Saji. （口頭）One-flow synthesis of N-succinimidyl 4-[18F]fluorobenzoate using a single microfluidic chip. The 2015 International Chemical Congress of Pacific Basin Societies (Hawaii, USA). 2015.12.
  4. Akira Makino, Ayaka Tomoike, Hiroyuki Kimura, Masahiro Ono, Hidehiko Okazawa, Yasushi Kiyono, Hideo Saji. （ポスター）Micelle type dual imaging probe for positron and near-infrared fluorescence imagings. The 2015 International Chemical Congress of Pacific Basin Societies (Hawaii, USA). 2015.12.

シンポジウム、ワークショップ及び講演

  1. 木村寛之．（講演・口頭）：放射性医薬品の標的臓器への集積．新規医療イノベーションのためのシンポジウム2015(大阪)，2015.10.
  2. 木村寛之．（講演・口頭）：膵β細胞量の定量化を目的とした分子イメージングプローブの開発研究． 第3回メタロミクスサマースクール(兵庫)，2015.8-9.
  3. 木村寛之，小野正博，佐治英郎．（講演・口頭）：膵β細胞膜上に発現するGLP-1受容体結合性イメージングプローブの開発．PETサマーセミナー2015 in 東京ベイ(千葉)，2015.9.

その他の印刷物(解説、プロシーディング等)

解説

  1. 木村寛之，佐治英郎．膵β細胞イメージングの可能性とプローブ開発状況,　「PETジャーナル」, 第31号, 22-24 （2015)

プロシーディング

  1. 稲垣暢也,　藤田直尚,　木村寛之,　浜松圭太,　佐野絋平,　平井光春,　村上　淳,　佐治英郎,　藤本裕之.　糖尿病の先制医療,　日本内科学会雑誌, 104, 1803-1807 (2015).
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