2019年

業績目録

原著

1. Non-invasive longitudinal quantification of beta cell mass with ¹¹¹Indium-labeled exendin-4. Naotaka Fujita, Hiroyuki Fujimoto, Keita Hamamatsu, Takaaki Murakami, Hiroyuki Kimura, Kentaro Toyoda, Saji Hideo, Nobuya Inagaki. The FASEB Journal, doi: 10.1096/fj.201900555RR (2019)
2. Evaluation of [¹⁸F]pitavastatin as a positron emission tomography probe for in vivo organic transporter polypeptide function. Yusuke Yagi, Hiroyuki Kimura*, Haruka Okuda, Kenji Arimitsu, Masahiro Ono, Yuji Nakamoto, Kaori Togashi, Hideo Saji. Nuclear Medicine and Biology, 74-75, 25-31 (2019)
3. Development of ^99mTc radiolabeled A85380 derivatives targeting cerebral nicotinic acetylcholine receptor: Novel radiopharmaceutical ligand ^99mTc-A-YN-IDA-C4. Daisuke Mori, Hiroyuki Kimura*, Hidekazu Kawashima, Yusuke Yagi, Kenji Arimitsu, Masahiro Ono, Hideo Saji. Bioorganic & Medicinal Chemistry, 27(18), 4200-4210 (2019)
4. Evaluation of Transporter-Mediated Hepatobiliary Transport of Newly Developed ¹⁸F-labeled Pitavastatin Derivative, PTV-F1, in Rats by PET Imaging. Hiroyuki Kimura*, Yusuke Yagi, Mutsumi Mikamo, Kazuya Maeda, Shinya Kagawa, Kenji Arimitsu, Tatsuya Higashi, Ryuichi Nishii, Masahiro Ono, Yuji Nakamoto, Kaori Togashi, Hiroyuki Kusuhara and Hideo Saji. Drug Metabolism and Pharmacokinetics, 34(5), 317-324 (2019)
5. Synthesis and biological evaluation of Tc-99m-cyclopentadienyltricarbonyl-technetium-labeled A-85380: An imaging probe for single-photon emission computed tomography investigation of nicotinic acetylcholine receptors in the brain. Hiroyuki Kimura, Masashi Ueda, Hidekazu Kawashima, Kenji Arimitsu, Yusuke Yagi, Hideo Saji. Bioorganic & Medicinal Chemistry, 27(11), 2245-2252 (2019)
6. Stability of distribution of F18 flurpiridaz after transient coronary occlusion in pigs. Rudolf A. Werner, Kazuhiro Koshino, Kenji Arimitsu, Constantin Lapa, Mehrbod S. Javadi, Steven P. Rowe, Naoko Nose, Hiroyuki Kimura, Kenji Fukushima, and Takahiro Higuchi. JACC: Cardiovascular Imaging, 12(11) Part 1, (doi: 10.1016/j.jcmg.2019.05.018) (2019)
7. Efficient gallium-68 radiolabeling reaction of DOTA derivatives using a resonant-type microwave reactor. Yusuke Yagi, Yoichi Shimizu, Kenji Arimitsu, Yuji Nakamoto, Takahiro Higuchi, Kaori Togashi, Hiroyuki Kimura*. Journal of Labelled Compounds and Radiopharmaceuticals, 62(3):132-138 (2019)
8. Initial clinical evaluation of PET/CT with ¹⁸F-FSU-880 targeting prostate-specific membrane antigen. Tsuneo Saga, Yuji Nakamoto, Takayoshi Ishimori, Takahiro Inoue, Yoichi Shimizu, Hiroyuki Kimura, Shusuke Akamatsu, Takayuki Goto, Hiroyuki Watanabe, Kosuke Kitaguchi, Masao Watanabe, Masahiro Ono, Hideo Saji, Osamu Ogawa, Kaori Togashi. Cancer Science, 110(2):742-750 (2019)
9. Syntheses and evaluation of a homologous series of aza-vesamicol as improved radioiodine-labeled probes for sigma-1 receptor imaging. Kazuma Ogawa, Ryohei Masuda, Kenji Mishiro, Mengfei Wang, Takashi Kozaka, Kazuhiro Shiba, Seigo Kinuya, Akira Odani. Bioorganic & Medicinal Chemistry, 27, 1990-1996 (2019), 10.1016/j.bmc.2019.03.054.

国際及び国内学会発表

1. 髙橋茉衣夏, 小阪孝史, 北村陽二, 池田朝海, 小川数馬, 柴 和弘.（ポスター） 「(+)-[^125/123I]OI5Vのシグマ-1受容体イメージング剤としての基礎的評価」, 第59回日本核医学会学術総会（松山）, 2019年11月1-3日.

シンポジウム、ワークショップ及び講演

1. 木村寛之．（講演・口頭）：PET化学 応用編「¹⁸F-PSMA 京大の取組」. PET化学ワークショップ2019 (神奈川), 2019.02.

その他の印刷物(解説、プロシーディング等)

解説

1. 木村寛之．がんの早期発見・早期治療を目指したセラノスティクス創薬,　Pharm Stage, Vol.18, No11 62-65 (2019)