2020年

業績目録

原著

Dendrimer-based micelles targeted to sites of active bone turnover for the effective treatment of bone metastasis. Shugo Yamashita, Hidemasa Katsumi, Erika Shimizu, Yuto Nakao, Hiroyuki Kimura, Toshiyasu Sakane, Akira Yamamoto. European Journal of Pharmaceutics and Biopharmaceutics, 157, 85-96 (2020)
Synthesis of ¹⁸F-labeled streptozotocin derivatives and an in-vivo kinetics study using positron emission tomography. Kenji Arimitsua, Yusuke Yagi, Kazuhiro Koshino, Yukina Nishito, Takahiro Higuchi, Hiroyuki Yasui, Hiroyuki Kimura*. Bioorganic & Medicinal Chemistry Letters, 30, 127400 (2020)
Efficacy of panitumumab and cetuximab in patients with colorectal cancer previously treated with bevacizumab; a combined analysis of individual patient data from ASPECCT and WJOG6510G. Hiroya Taniguchi, Takeharu Yamanaka, Daisuke Sakai, Kei Muro, Kentaro Yamazaki, Susume Nakata, Hiroyuki Kimura, Paul Ruff Tae Won Kim, Marc Peeters and Timothy Price. Cancers, 12, 1715 (2020)
¹⁸F-Labeled PSMA-Targeted Radiotracers: Leveraging the Advantages of Radiofluorination for Prostate Cancer Molecular Imaging. Rudolf A. Werner, Constantin Lapa, Sara Sheikbahaei, Takahiro Higuchi, Frederik L. Giesel, Spencer Behr, Alexander Drzezga, Hiroyuki Kimura, Andreas K. Buck, Martin G. Pomper, Michael A. Gorin, Steven P. Rowe. Theranostics, 10(1), 1-16 (2020)
S-nitrosylated L-serine-modified dendrimer for kidney-targeted nitric oxide delivery and prevention of renal ischemia/reperfusion. Hidemasa Katsumi, Rie Takashima, Hiroe Suzuki, Natsuko Hirai, Satoru Matsuura, Hiroyuki Kimura, Masaki Morishita and Akira Yamamoto. Free Radical Research, vol.54, NOS. 11-12, 841-847, doi: 10.1080/10715762.2019.1697437 (2020)
Development and characterization of a ⁶⁸Ga-labeled A20FMDV2 peptide probe for the PET imaging of αvβ6 integrin-positive pancreatic ductal adenocarcinoma. Takashi Ui, Masashi Ueda, Yusuke Higaki, Shinichiro Kamino, Kohei Sano, Hiroyuki Kimura, Hideo Saji, Shuichi Enomoto. Bioorganic & Medicinal Chemistry, 28, 115189 (2020)
Initial evaluation of AF78: A rationally designed fluorine-18-labelled PET radiotracer targeting norepinephrine transporter. Xinyu Chen, Alexander Fritz, Rudolf A. Werner, Naoko Nose, Yusuke Yagi, Hiroyuki Kimura, Steven P. Rowe, Kazuhiro Koshino, Michael Decker, Takahiro Higuchi. Molecular Imaging and Biology, 22(3), 602-611 (2020)
(-)-o-[¹¹C]methyl-trans-decalinvesamicol ((-)-[¹¹C]OMDV) as a PET ligand for the vesicular acetylcholine transporter. Daisuke Miwa, Yoji Kitamura, Takashi Kozaka, Taiki Shigeno, Kazuma Ogawa, Junichi Taki, Seigo Kinuya, Kazuhiro Shiba. Synapse, 74, e22176 (2020), 10.1002/syn.22176.
Combination of gemcitabine and anti-PD-1 antibody enhances the anticancer effect of M1 macrophages and the Th1 response in a murine model of pancreatic cancer liver metastasis. Tuyen Thuy Bich Ho, Alessandro Nasti, Akihiro Seki, Takuya Komura, Hiiro Inui, Takashi Kozaka, Yoji Kitamura, Kazuhiro Shiba, Taro Yamashita, Tatsuya Yamashita, Eishiro Mizukoshi, Kazunori Kawaguchi, Takashi Wada, Masao Honda, Shuichi Kaneko, Yoshio Sakai. Journal for immunotherapy of cancer, 8, e001367, 1-12, Citations: 1 (2020), 10.1136/jitc-2020-001367.

著書

Handbook of In Vivo Chemistry in Mice: From Lab to Living System, Wiley VCH (2020年1月29日発売)

Yusuke Yagi, Hidekazu Kawashima, Kenji Arimitsu, Koki Hasegawa, Hiroyuki Kimura*: Chapter 6. Single-Photon Emission Computed Tomographic Imaging in Live Animals., pp.151-184,
Koki Hasegawa, Hidekazu Kawashima, Yusuke Yagi, Hiroyuki Kimura*: Chapter 7. Radiotherapeutic Applications., pp.185-208,

Chapter 6，7の執筆と編集を担当。

国際及び国内学会発表

阿部公香，高橋茉衣夏，小阪孝史，北村陽二，小川数馬，柴和弘.（ポスター, 新型コロナウイルス感染症の影響により，みなし開催となった）, 光学活性体(+)-[^125/123I]OI5Vのシグマ-1受容体(σ-1R)イメージング剤としての評価. 日本薬学会第140回年会（京都）, 2020年3月25-28日.
野坂朋代, 池田朝海, 北村陽二, 小阪孝史, 小川数馬, 柴和弘. （ポスター, 新型コロナウイルス感染症の影響により，みなし開催となった）, ストレス負荷マウスにおけるストレス強度と局所脳血流量の関係. 日本薬学会第140回年会（京都）, 2020年3月25-28日.

その他の印刷物(解説、プロシーディング等)

紀要

髙尾郁子，木村徹，千原佳子，有光健治，内藤行喜，木村寛之，河野享子，平山恵津子，徳山友紀，安井裕之，藤原洋一．学生実習に取り入れたピア評価による実技検定の実践と学生の意識変化, 京都薬科大学紀要, 1: 103-112 (2020), doi: 10.34445/00000223